Plasma Renin Activity (PRA)

Analyte [material]

Plasma renin activity (PRA) [P]

Reference range, target level, or decision threshold

0.15-2.15 nmol/L/h (0.2-2.8 ng/mL/h) at rest (supine)!

[nmol/L] × 1.33 = [ng/mL]

Interpretation of results

↑ Renovascular hypertension, malignant hypertension, renin-secreting tumors, hypovolemia, cirrhosis, Addison disease, Bartter syndrome

↓ Primary hyperaldosteronism, high-sodium diet, glucocorticoid therapy