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For a brief introduction and guide to abbreviations, see Laboratory Tests: General Remarks.
Antithrombin (AT) function [P]
Reference range, target level, or decision threshold
0.83-1.28 U/mL!!!; LD
AT immunoassay is also available as a specialty test.
Interpretation of results
↑ or falsely normal with direct factor Xa inhibitors for anti-Xa AT assays or with direct thrombin inhibitors for anti-IIa AT assays
↓ Congenital antithrombin deficiency, consumptive states (eg, acute thrombosis, DIC, sepsis), liver disease, nephrotic syndrome, malnutrition, protein-losing enteropathies, pregnancy, UFH treatment
