C-Reactive Protein (CRP)

How to Cite This Chapter: Don-Wauchope A, Chetty VT, Ivica J, Kavsak P, Khan WI, Lafreniere M, Nouri K, Solnica B. C-reactive Protein (CRP). McMaster Textbook of Internal Medicine. Kraków: Medycyna Praktyczna. https://empendium.com/mcmtextbook/chapter/B31.1269.3.7.49. Accessed December 05, 2025.
Last Reviewed: May 9, 2022
Last Updated: May 9, 2022
Chapter Information

For a brief introduction and guide to abbreviations, see Laboratory Tests: General Remarks.

Analyte [material]

C-reactive protein (CRP) [S/P]

Reference range, target level, or decision threshold

0.08-3.1 mg/L!!!; CPG

Cutoff value for acute phase response: 10 mg/L!!!; CPG

Cardiovascular risk cutoff: 2 mg/L!!!; CPG

Interpretation of results

↑ Infections, systemic connective tissue diseases, IBD, acute pancreatitis, MI, after surgery, malignancies

Minor ↑ tobacco smoking, increased body weight, atherogenic dyslipidemia, type 2 DM, arterial hypertension, hormone replacement therapy

Cardiovascular risk evaluation: <1 mg/L, low; 1-3 mg/L, moderate; >3 mg/L, high

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