How to Cite This Chapter: Don-Wauchope A, Chetty VT, Ivica J, Kavsak P, Khan WI, Lafreniere M, Nouri K, Solnica B. Aldosterone. McMaster Textbook of Internal Medicine. Kraków: Medycyna Praktyczna. https://empendium.com/mcmtextbook/chapter/B31.1269.3.7.5. Accessed October 06, 2024.
Last Updated: May 9, 2022
Last Reviewed: May 9, 2022
Chapter Information
McMaster Textbook of Internal Medicine Editorial Offices
Editorial Office (Canada)
Authors: Andrew Don-Wauchope, Vasudhevan T. Chetty, Joško Ivica, Peter Kavsak, Waliul I. Khan, Matthew Lafreniere, Kazem Nouri
Editorial Office (Poland)
Authors: Bogdan Solnica
For a brief introduction and guide to abbreviations, see Laboratory Tests: General Remarks.
Analyte [material]
Aldosterone [P/U24h]
Reference range, target level, or decision threshold
140-555 pmol/L (5-20 ng/dL) at rest (supine)!!!
[ng/dL] × 27.7 = [pmol/L]
14-53 nmol/24 h (5-19 microg/24 h)!!!
[microg] × 2.8 = [nmol]
Interpretation of results
↑ Primary hyperaldosteronism, secondary hyperaldosteronism (renovascular hypertension, malignant hypertension, renin-secreting tumors, hypovolemia, cirrhosis, nephrotic syndrome, heart failure), Bartter syndrome
↓ Primary adrenal insufficiency, high-sodium diet, glucocorticoid therapy