How to Cite This Chapter: Don-Wauchope A, Chetty VT, Ivica J, Kavsak P, Khan WI, Lafreniere M, Nouri K, Solnica B. Aldosterone. McMaster Textbook of Internal Medicine. Kraków: Medycyna Praktyczna. Accessed May 24, 2024.
Last Updated: May 9, 2022
Last Reviewed: May 9, 2022
Chapter Information

For a brief introduction and guide to abbreviations, see Laboratory Tests: General Remarks.

Analyte [material]

Aldosterone [P/U24h]

Reference range, target level, or decision threshold

140-555 pmol/L (5-20 ng/dL) at rest (supine)!!!

[ng/dL] × 27.7 = [pmol/L]

14-53 nmol/24 h (5-19 microg/24 h)!!!

[microg] × 2.8 = [nmol]

Interpretation of results

↑ Primary hyperaldosteronism, secondary hyperaldosteronism (renovascular hypertension, malignant hypertension, renin-secreting tumors, hypovolemia, cirrhosis, nephrotic syndrome, heart failure), Bartter syndrome

↓ Primary adrenal insufficiency, high-sodium diet, glucocorticoid therapy

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