Cholesterol, High-Density Lipoprotein (HDL-C)

How to Cite This Chapter: Don-Wauchope A, Chetty VT, Ivica J, Kavsak P, Khan WI, Lafreniere M, Nouri K, Solnica B. Cholesterol, High-density Lipoprotein (HDL-C). McMaster Textbook of Internal Medicine. Kraków: Medycyna Praktyczna. https://empendium.com/mcmtextbook/chapter/B31.1269.3.7.57. Accessed December 05, 2025.
Last Reviewed: May 9, 2022
Last Updated: May 9, 2022
Chapter Information

For a brief introduction and guide to abbreviations, see Laboratory Tests: General Remarks.

Analyte [material]

Cholesterol, high-density lipoprotein (HDL-C) [S/P]

Reference range, target level, or decision threshold

Men: >1.0 mmol/L (40 mg/dL)

Women: >1.3 mmol/L (50 mg/dL)

[mmol/L] × 38.5 = [mg/dL]

Interpretation of results

↓ Atherogenic dyslipidemia, familial hypoalphalipoproteinemia (apolipoprotein A1 deficiency), Tangier disease (deficiency of intracellular cholesteryl ester transfer protein [CETP], ABCA1 protein), familial lecithin-cholesterol acyltransferase (LCAT) deficiency, fish-eye disease (partial LCAT deficiency)

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