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For a brief introduction and guide to abbreviations, see Laboratory Tests: General Remarks.
Activated partial thromboplastin time (aPTT) [P]
Reference range, target level, or decision threshold
26-40 s (depending on reagents used)!!!; LD
Interpretation of results
↑ Congenital or acquired deficiencies of fibrinogen and/or factors II, V, VIII (eg, hemophilia, von Willebrand disease), IX, XI, or XII; acquired inhibitors against factors VIII (acquired hemophilia A), IX, XI, or XII, high-molecular weight kininogen, or prekallikrein; vitamin K deficiency; liver diseases; DIC; hemodilution; lupus anticoagulant; anticoagulants (UFH, VKAs, direct thrombin inhibitors, direct factor Xa inhibitors)
