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Do thyroid-stimulating hormone (TSH) levels change with age? Should we use different criteria to diagnose and treat hypothyroidism in the elderly?
René Rodríguez-Gutiérrez:
Now we know for sure that happens. Definitely TSH varies and elevates with age. It has been suggested, even though we do not have a clear cutoff, that in patients above 65 or 70 years of age, probably the cutoff is between 7 and 8 mIU/L. I think definitely these patients will not need to be treated when they are in that range.
First-line therapy in type 2 diabetes
What is the first-line therapy in type 2 diabetes mellitus: metformin as monotherapy or combined treatment with 2 or more oral antidiabetic agents?