Follow-up hormonal tests in nonfunctioning adrenal incidentaloma

How often should hormonal laboratory tests be repeated in the follow-up of a patient with an initially nonfunctioning adrenal incidentaloma?

René Rodríguez-Gutiérrez: That is a very interesting question. I will say there is a lot of controversy for this question. We do not have enough data, good-quality evidence to respond to that question. However, most experts will recommend to test ideally on a yearly basis only for Cushing syndrome, while once you rule out pheochromocytoma or if the patient has hypertension and you rule out aldosteronism, one measure will be enough.