Sepsis: No response to the initial fluid bolus

Emilie Belley-Côté

How to manage a patient with sepsis not responding to the initial intravenous (IV) fluid bolus?

Emilie Belley-Côté, MD: If they do not respond to the first bolus, I tend to give another bolus. Once I have given 2 or 3 L of fluids, I move on to starting vasopressors. Then my first line tends to be norepinephrine, and then vasopressin.

We would love to hear from you

  • Do you have any comments?
  • Have you found a mistake?
  • Would you like to suggest a feature?

We use cookies to ensure you get the best browsing experience on our website. Refer to our Cookies Information and Privacy Policy for more details.