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Do we have enough evidence to always prefer balanced crystalloids over normal saline in patients with kidney injury?
Jürgen Floege, MD:
No, not really. There is evidence that only giving sodium chloride can induce harm, mostly via the chloride. But the evidence also suggests that you need very large amounts, 3 L or more, and that the risk in general is relatively low.
So with balanced solutions yes, you can be on the safer side, but I think it is overstating that you should by all means avoid sodium chloride.
Theophylline in COPD
Should theophylline be abandoned in patients with chronic obstructive pulmonary disease? Even a recent study with low-dose theophylline on top of inhaled corticosteroids/long-acting beta-agonists has not shown any positive effects.
Nephrotic syndrome in adults: current management
A lecture by Dr Jürgen Floege, from RWTH Aachen University, Germany, delivered at McMaster International Review Course in Internal Medicine in Kraków in May 2017.
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