Heterogeneity in the population of patients with cancer of unknown primary

Is the population of patients with cancer of unknown primary heterogeneous? What malignancies dominate in this group?

Nicholas Pavlidis: If you look histologically, the most common ones, constituting up to 80% of cases, are adenocarcinomas, 10% are squamous cell carcinomas, and the rest are undefined neoplasms. So the most common one histologically is adenocarcinoma. But, as I said before, we split these subsets into the good and the bad prognosis. The most common cancer histologically is adenocarcinoma, and the most common prognosis is the poor prognosis.