Reducing fracture risk in osteoporosis

Jonathan Adachi

Does treatment really reduce fracture risk in patients with osteoporosis?

Jonathan Adachi: Treatment does reduce fractures. If you look at the gold standard of trials, of research, we know that randomized, double-blind, placebo-controlled trials have shown that we can reduce fractures anywhere from 50% to 70%. A spine fracture reduction by 50% to 70% is not an inconsequential number. When we take a look at hip fractures, in general we can see about a 40% reduction in hip fractures. And when it comes down to nonvertebral fractures, it is anywhere from 20% and 30%. So the clinical trials, the evidence – solid evidence – reveals that we can reduce the risk of fracture.

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