Dr Gordon Guyatt is a distinguished professor at McMaster University who played a fundamental role in defining the concept and advancing the methodology of evidence-based medicine. He was instrumental in introducing the GRADE approach for evaluating quality of evidence and strength of recommendations, now adopted by over 90 organizations worldwide. He has played a key role in over 40 major clinical studies. One of the world’s most cited researchers with over 1000 peer-reviewed publications. Member of the editorial team of the McMaster Textbook of Internal Medicine.