ArticlesHuman-important outcomes and EBM during the COVID-19 pandemic The pandemic brought with it an entire new realm of human suffering that is only indirectly related to disease itself—it relates to the societies’ ways of dealing with the illness. We propose that when making decisions about health-care interventions during this and during future pandemics, those “human-important outcomes” are carefully considered.
ArticlesTargeting blood pressure in people with diabetes mellitus This review examines different blood pressure targets in patients with diabetes mellitus discussed in a number of trials and papers, including the ACCORD and SPRINT trials as well as various recent meta-analyses.
ArticlesDiagnosis and therapy of antiphospholipid syndrome The review grades the diagnosis of antiphospholipid syndrome (APS) and discusses secondary prevention of thrombotic APS, prevention of pregnancy morbidity, treatment of catastrophic APS, and new tools in laboratory diagnosis and treatment.
UpdatesChapter on COVID-19 now available A new chapter discussing coronavirus disease 2019 (COVID-19) has been added to the online edition and mobile apps of the McMaster Textbook of Internal Medicine.
ArticlesPredicting short- and long-term mortality in patients with pulmonary embolism An adequate evaluation of the prognosis in patients with pulmonary embolism may guide decision-making in terms of the intensity of the initial treatment during the acute phase, duration of treatment, and intensity of follow-up control visits in the long term.
UpdatesMetaClinician: Iodine vs chlorhexidine Do you ever wonder what your colleagues would do in a similar clinical situation? Join the MetaClinician® hive mind to ask your questions, check your understanding of new evidence, and earn CME credits. This module focuses on iodine vs chlorhexidine as skin antiseptics.
Rapid RefreshersUrinary tract infection (UTI) Urinary tract infection (UTI): important points to guide the assessment and management of patients. Published: 2020-04-28