Serum Proteins, Electrophoresis

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Serum proteins, electrophoresis [S]

Reference range, target level, or decision threshold

Albumin: 4.0-5.3 g/dLCW

alpha1-Globulin: 0.13-0.28 g/dLCW

alpha2-Globulin: 0.38-0.7 g/dLCW

beta-Globulins: 0.65-1.1 g/dLCW

gamma-Globulins: 0.5-1.2 g/dLCW

Interpretation of results

See Albumin, Immunoglobulins

↑ alpha1, alpha2: acute inflammation

↑ beta, gamma: chronic inflammation, liver diseases

↑ gamma: IgG or IgM monoclonal gammopathies (eg, multiple myeloma)

↑ beta: IgA monoclonal gammopathies

↑ alpha2, beta, and ↓ gamma: nephrotic syndrome

↓ gamma: hypogammaglobulinemia

↓ alpha1: alpha1-antitrypsin deficiency