Sodium Disturbances

How to Cite This Chapter: Mathew A, Kokot F, Franek E, Drabczyk R. Sodium Disturbances. McMaster Textbook of Internal Medicine. Kraków: Medycyna Praktyczna. https://empendium.com/mcmtextbook/chapter/B31.II.19.1.3. Accessed December 05, 2021.
Last Updated: June 14, 2018
Last Reviewed: May 17, 2019
Chapter Information

Physiologic BackgroundTop

The body of an average adult weighing 70 kg contains ~4200 mmol (~60 mmol/kg) of sodium. A total of 91% of the body sodium is in the extracellular fluid (ECF) and the remainder is the intracellular fluid (ICF).

Dietary sodium intake is 80 to 160 mmol/d. In individuals with a normal sodium balance, 95% of dietary sodium is filtered into the renal tubule, 4.5% with feces, and 0.5% through the skin. Less than 1% of sodium filtered into the renal tubule is excreted with urine, while the remaining sodium is reabsorbed.

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