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Hamartomatous polyps are rare findings that can present as:
1) Juvenile polyps: These can occur at any age but are more often diagnosed in children, in whom they are the most common type of polyps and the most common cause of intestinal bleeding. They are usually found in small numbers in the rectum or sigmoid colon and do not increase the risk of colorectal cancer. However, they may also present as a large number of polyps (see Juvenile Polyposis Syndrome).
2) Peutz-Jeghers polyps: These nonmalignant lesions can occur in any part of the gastrointestinal tract, most often in the small intestine. They are usually found in young adults with associated symptoms such as rectal bleeding, anemia, and intussusception. Detailed characteristics: see Peutz-Jeghers Syndrome.
3) Polyps in congenital PTEN hamartoma tumor syndromes (including Cowden syndrome): A group of rare diseases with different clinical features, characterized by increased risk of cancer, especially breast, thyroid, uterine, kidney, and colon cancers.
