McMaster Textbook of Internal Medicine

McMaster Textbook of Internal Medicine
Interviews
Cardiology
PCSK9 inhibitors in secondary prevention of MI

PCSK9 inhibitors in secondary prevention of MI

2018-09-04

Gerd Hasenfuß

Recorded at the 4th McMaster International Review Course in Internal Medicine (MIRCIM).

In which patients should proprotein convertase subtilisin/kexin type 9 (PCSK9) inhibitors be used in the secondary prevention of myocardial infarction (MI)?

Gerd Hasenfuß, MD: These are the new drugs to lower cholesterols and they should be used in patients at high risk, in particular those with other sclerotic cardiovascular disease where the goal of the low-density lipoprotein (LDL) level of 70 mg/dL cannot be reached with statins and ezetimibe. In those patients the PCSK9 inhibitors should be used in addition. Another option would be to use them in patients who are not tolerant of statins.

See also

Secondary prevention of cardiovascular diseases: current state-of-art A lecture by Dr Gerd Hasenfuß, from the University of Göttingen, Germany, delivered at McMaster International Review Course in Internal Medicine in Kraków in May 2018.
Heart failure: Diagnosis of rare causes Which patients with heart failure should undergo a thorough diagnosis of rare causes of heart failure such as myopathy or storage diseases?
Invasive treatment in STEMI: PCI of the culprit vessel vs a multivessel approach Which invasive treatment strategy is preferred in ST-segment elevation myocardial infarction (STEMI): PCI of the infarct-related artery only or revascularization of all significant lesions?
Hypertension in the elderly and universal BP targets Dr Franz H. Messerli discusses treatment of hypertension in the elderly patients, the idea of setting universal blood pressure targets, and the results of SPRINT in a conversation with Dr Jerzy Gąsowski.
Tolerance and adverse effects of PCSK9 inhibitors What are the tolerance and adverse effects of proprotein convertase subtilisin/kexin type 9 inhibitors?
Managing NSTE acute coronary syndromes in 2016 A lecture by Prof. Sanjit Jolly, from McMaster University, Canada, delivered at McMaster International Review Course in Internal Medicine in Kraków in May 2016.
How to prevent a cardiovascular event A lecture by Prof. Salim Yusuf, from McMaster University, Canada, delivered at McMaster International Review Course in Internal Medicine in Kraków in May 2016.

We would love to hear from you

Comments, mistakes, suggestions?

We use cookies to ensure you get the best browsing experience on our website. Refer to our Cookies Information and Privacy Policy for more details.