Desirable bacterial strains in FMT

2018-05-04

Christine Lee

What bacterial strains should be present in fecal material used for fecal microbiota transplantation (FMT)? Do you select a donor on the basis of the bacterial strains present in the fecal material?

Christine Lee: There are many unknowns which are related to FMT. When we have done the metagenomics, we were able to identify approximately 20 bacteria that are consistently present in individuals who have had successful FMT.

[As to selecting donors based on bacterial strains,] we have not yet done that, but through our experience we know that when stool of certain individuals is used, the recipients achieve higher cure rates.

See also

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Patients at highest risk of C difficile infection What patients are at the highest risk of developing Clostridium difficile infection?
Diagnosing H pylori-associated dyspepsia After the publication of the Kyoto global consensus report, we are faced with a new entity called Helicobacter pylori-associated dyspepsia. How to make an appropriate diagnosis of this condition?
Antibiotic resistance: how to handle in clinical practice A lecture by Prof. Mark Loeb, from McMaster University, Canada, delivered at McMaster International Review Course in Internal Medicine in Kraków in May 2016.
Testing for H pylori infection Which patients should be tested for Helicobacter pylori infection?
Fecal microbiota transplantation in gastrointestinal diseases A review of the use of fecal suspension in saline as treatment of choice to terminate relapsing and severe Clostridium difficile infection.
Treating patients with HCV infection Who should treat patients with HCV infection? General practitioners, infectious disease specialists, hepatologists?

Desirable bacterial strains in FMT

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