McMaster Textbook of Internal Medicine

McMaster Textbook of Internal Medicine
Interviews
Gastroenterology
Duration of PPI treatment in functional dyspepsia

Duration of PPI treatment in functional dyspepsia

2018-06-08

Paul Moayyedi

What should be the duration of proton pump inhibitor (PPI) treatment in patients with functional dyspepsia?

Paul Moayyedi: I normally continue for 2 months and then stop. That is just my practice. Most of the studies are 2 to 4 weeks. If we are getting benefit, I like to carry on a little longer and then stop and see if the patient still needs it. If they do, they can start it again, but they should try stopping PPI every 6 months. Functional dyspepsia is a waxing and waning condition, so when we are at a quiet period, we do not need to be taking PPIs.

See also

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Scoring systems for cirrhosis What prognostic tools or scoring systems are most useful in patients with cirrhosis?
Red flags in dyspepsia When should dyspepsia become a clinical concern? What are the high-risk groups or red flags that should never be ignored in patients with dyspepsia?
NOACs and the rate of GI bleeding worldwide It has already been several years since the wide adoption of new oral anticoagulants, such as dabigatran or rivaroxaban. Are we able to estimate how it has influenced the rate of gastrointestinal bleeding (GI) worldwide?
Current management of acute nonvariceal GI bleeding A lecture by Dr Janusz Jankowski, from University of Central Lancashire, UK, delivered at McMaster International Review Course in Internal Medicine in Kraków in May 2017.
Patient with laryngitis or cough and suspicion of GERD What findings in history or physical examination in a patient with laryngitis or chronic cough should raise the suspicion of gastroesophageal reflux disease (GERD)?
Biosimilar drugs in Canada Do you use biosimilar drugs in Canada?

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