Treatment available for symptomatic GERD

What pharmacological treatment should be used in patients with symptoms of gastroesophageal reflux disease?

Janusz Jankowski, MD, PhD: There are 4 different choices available to most people. It starts off with prn (as-needed)—take it as you have symptoms—proton pump inhibitors (PPIs). Low-dose PPIs once a day, low-dose PPIs twice a day, and high-dose PPIs twice a day.

Most patients who have been weaned off PPIs will be on a prn basis. Most other of the new patients will be on either low-dose PPIs once a day or low-dose twice a day. We reserve the high-dose PPIs for twice daily treatment for people with severe symptoms or severe esophagitis.

See also

Current management of dyspepsia A lecture by Dr Paul Moayyedi, from McMaster University, Canada, delivered at McMaster International Review Course in Internal Medicine in Kraków in May 2017.
Preferred treatment in symptomatic GERD What is your preferred treatment in patients with symptoms of gastroesophageal reflux disease?
Opioids in the treatment of chronic pain A lecture by Dr Jenny Legassie, from McMaster University, Canada, delivered at McMaster International Review Course in Internal Medicine in Kraków in May 2017.
Main causes of cirrhosis nowadays What are the main causes of cirrhosis nowadays?
Evaluating H pylori eradication When should we check if Helicobacter pylori eradication therapy was successful? In particular, should we do it in patients with dyspepsia?
FMT: Mode of delivery, use in ulcerative colitis How do you perform fecal microbiota transplantation (FMT)? What is your experience with FMT in ulcerative colitis?

Treatment available for symptomatic GERD

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