McMaster Textbook of Internal Medicine

McMaster Textbook of Internal Medicine
Interviews
Gastroenterology
New treatment options for ulcerative proctitis and colitis

New treatment options for ulcerative proctitis and colitis

2023-10-16

Paul Moayyedi

Recorded at the 8th McMaster International Review Course in Internal Medicine (MIRCIM).

Paul Moayyedi, MB, is a professor of medicine, assistant dean of research, and director of the Farncombe Family Digestive Health Research Institute in the Faculty of Health Sciences at McMaster University.

Are there any new drugs available for the local (rectal) treatment of ulcerative proctitis?

Specifically for ulcerative proctitis, I wouldn't say they are any new therapies, but for ulcerative colitis, yes. The Janus kinase (JAK) 2 inhibitors are relatively new on the market and oral therapy, small-molecule therapy, for ulcerative colitis can be beneficial and works in a different way from other biologic therapies for this condition.

See also

The ABCs of high-quality colonoscopy What conditions must be met for a screening colonoscopy to be considered reliable? When should a follow-up colonoscopy be performed sooner than indicated by the surveillance schedule and how long after initial examination?
Recent advances in the management of NAFLD If you were to name the 3 most important recent advances in the management of NAFLD that are relevant for everyday practice, what would they be?
H pylori eradication and allergy to metronidazole or fluoroquinolones What treatment regimen should be used for Helicobacter pylori eradication in patients with allergy to metronidazole or with allergy to fluoroquinolones (as the first choice and in case of initial treatment failure)?
The 3 most important recent advances in the management of gastrointestinal motility disorders Dr Irene Sarosiek from Texas Tech University Health Sciences Center (TTUHSC), United States, offers her view on the 3 most important recent advances in the management of GI motility disorders.
Fecal transplantation beyond C difficile A lecture by Dr Paul Moayyedi, from McMaster University, Canada, delivered at McMaster International Review Course in Internal Medicine (MIRCIM) in May 2019.

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