McMaster Textbook of Internal Medicine

McMaster Textbook of Internal Medicine
Interviews
Nephrology
NSAIDs and the risk of kidney injury

NSAIDs and the risk of kidney injury

2019-01-23

Jürgen Floege

Recorded at the 4th McMaster International Review Course in Internal Medicine (MIRCIM).

Which nonsteroidal anti-inflammatory drugs (NSAIDs) present the highest risk of causing kidney injury?

Jürgen Floege, MD: They are all the same as far as I am concerned. Even the newer cyclooxygenase-2 (COX-2) inhibitors—which are certainly safer when it comes to gastric ulcers and so forth—can cause renal damage, because COX-2 is always present in the kidney, it is constitutively there. As far as I am concerned, they are all the same.

See also

Duration of treatment with high-dose PPIs in GERD What should be the duration of high-dose proton pump inhibitor (PPI) treatment in a patient with gastroesophageal reflux disease?
Current management of dyspepsia A lecture by Dr Paul Moayyedi, from McMaster University, Canada, delivered at McMaster International Review Course in Internal Medicine in Kraków in May 2017.
Biomarkers of AKI in clinical practice Is there any progress in the use of biomarkers of acute kidney injury (AKI) in clinical practice? Are we close to "kidney troponins"?
Antihypertensive drugs in patients on dialysis and those with CKD not on dialysis Which antihypertensive drugs are preferred in patients treated with hemodialysis and which in those with chronic kidney disease in whom hemodialysis is not yet indicated?
Balanced crystalloids vs normal saline in kidney injury Do we have enough evidence to always prefer balanced crystalloids over normal saline in patients with kidney injury?
Heart failure: Diagnosis of rare causes Which patients with heart failure should undergo a thorough diagnosis of rare causes of heart failure such as myopathy or storage diseases?
Nephrotic syndrome in adults: current management A lecture by Dr Jürgen Floege, from RWTH Aachen University, Germany, delivered at McMaster International Review Course in Internal Medicine in Kraków in May 2017.
Glomerulonephritis: an update A lecture by Prof. Jürgen Floege, from RWTH Aachen University, Germany, delivered at McMaster International Review Course in Internal Medicine in Kraków in May 2016.
Potassium levels requiring hospital admission In an outpatient setting, until what value of potassium can we let an ambulatory patient go home with indications? When is hospitalization mandatory?
Iatrogenic acute kidney injury A lecture by Dr Jürgen Floege, from RWTH Aachen University, Germany, delivered at McMaster International Review Course in Internal Medicine in Kraków in May 2018.

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