McMaster Textbook of Internal Medicine

Topical NSAIDs in gout

2018-07-24

George Nuki

Are topical nonsteroidal anti-inflammatory drugs effective in the treatment of gout?

George Nuki: I have no experience with that. Gout inflammation is so intense that I cannot think that it would have a major effect. It does have some real effect and it has some placebo effect. But I think gout is perhaps the one condition where one is not looking first of all to use topical agents. In osteoarthritis it can be very effective, safer perhaps than oral ones, but I would downplay that a little bit in patients with gout.

See also

Giant cell arteritis and other large vessel vasculitis A lecture by Dr Bhaskar Dasgupta, from Southend University Hospital, UK, delivered at McMaster International Review Course in Internal Medicine in Kraków in May 2017.
Behçet disease: Uncommon or underdiagnosed? Is Behçet disease uncommon or rather underdiagnosed? When should it be suspected?
Most common errors in the treatment of gout What are the most common errors in the treatment of gout?
Monitoring disease activity in GCA How to monitor disease activity in patients with giant cell arteritis (GCA)? Is it useful to measure interleukin 6 levels, or are inflammatory markers (ESR, CRP) sufficient?
Axial SpA: diagnostics, treatment, disease activity Dr Filip Van den Bosch, associate professor of rheumatology at Ghent University, Belgium, reviews the current diagnostic methods, treatment, and activity measurement used in patients with nonradiographic axial spondyloarthritis in a conversation with Dr Mariusz Korkosz.
Reducing fracture risk in osteoporosis Does treatment really reduce fracture risk in patients with osteoporosis?

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