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References
International Team for the Revision of the International Criteria for Behçet's Disease (ITR-ICBD). The International Criteria for Behçet's Disease (ICBD): a collaborative study of 27 countries on the sensitivity and specificity of the new criteria. J Eur Acad Dermatol Venereol. 2014 Mar;28(3):338-47. doi: 10.1111/jdv.12107. Epub 2013 Feb 26. PubMed PMID: 3441863.Blake T, Pickup L, Carruthers D, et al. Birmingham Behçet's service: classification of disease and application of the 2014 International Criteria for Behçet's Disease (ICBD) to a UK cohort. BMC Musculoskelet Disord. 2017 Mar 11;18(1):101. doi: 10.1186/s12891-017-1463-y. PubMed PMID: 28283043; PubMed Central PMCID: PMC5346254.
What is new in the 2014 International Criteria for Behçet Disease?
Gülen Hatemi, MD: In the new criteria the major organ involvements that were missing from the original criteria are included in order to increase the sensitivity of the criteria.
However, this new set of criteria has lower specificity, and this causes a lot of problems in areas of the world where the prevalence of Behçet syndrome is low. In a very recent study from Birmingham, the specificity of the new criteria was 19%, which I think is quite low to use as a diagnostic test.
