Dr Shervin Zandi, assistant clinical professor at the Department of Medicine, McMaster University, joins Dr Khalid Azzam during the Chair's Medical Grand Rounds to present a comprehensive review of the expanding role of sodium-glucose cotransporter-2 (SGLT-2) inhibitors in the treatment of diabetes, heart failure, and chronic kidney disease, as well as to discuss special considerations and precautions associated with these agents. The webinar was recorded on October 14, 2021.