Dr Kaveh G. Shojania, professor and vice chair of Quality & Innovation in the Department of Medicine at University of Toronto, joins Dr Seychelle Yohanna to discuss the marginal effects of most efforts and biomedical research on health-care quality improvement. The expert recognizes the importance of fundamental changes in research and policy to address global crises. The webinar was recorded at the Chair's Medical Grand Rounds on November 4, 2021.