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Here are the 3 articles chosen by McMaster editors as suggested reading for this week.
CHEST guideline: antithrombotic therapy for VTE
Kearon C, Akl EA, Ornelas J, et al. Antithrombotic Therapy for VTE Disease: CHEST Guideline and Expert Panel Report. Chest. 2016 Feb;149(2):315-52. doi: 10.1016/j.chest.2015.11.026. Epub 2016 Jan 7. PubMed PMID: 26867832.
This is the 2016 guideline update on antithrombotic therapy for venous thromboembolism published by the American College of Chest Physicians (CHEST).
Medical therapy +/- CABG in patients with CAD and low LVEF
Velazquez EJ, Lee KL, Jones RH, et al; STICHES Investigators. Coronary-Artery Bypass Surgery in Patients with Ischemic Cardiomyopathy. N Engl J Med. 2016 Apr 21;374(16):1511-20. doi: 10.1056/NEJMoa1602001. Epub 2016 Apr 3. PubMed PMID: 27040723.
Guyton RA, Smith AL. Coronary Bypass--Survival Benefit in Heart Failure. N Engl J Med. 2016 Apr 21;374(16):1576-7. doi: 10.1056/NEJMe1603615. Epub 2016 Apr 3. PubMed PMID: 27040599.
Guyton RA, Smith AL. Coronary Bypass--Survival Benefit in Heart Failure. N Engl J Med. 2016 Apr 21;374(16):1576-7. doi: 10.1056/NEJMe1603615. Epub 2016 Apr 3. PubMed PMID: 27040599.
This paper reviews the results of the Surgical Treatment for Ischemic Heart Failure Extension Study (STICHES), which compared the outcomes of medical therapy alone with added coronary-artery bypass grafting (CABG) in patients with heart failure and severe left ventricular dysfunction.
Surgival aortic valve replacement vs TAVR
Leon MB, Smith CR, Mack MJ, et al; PARTNER 2 Investigators. Transcatheter or Surgical Aortic-Valve Replacement in Intermediate-Risk Patients. N Engl J Med. 2016 Apr 28;374(17):1609-20. doi: 10.1056/NEJMoa1514616. Epub 2016 Apr 2. PubMed PMID: 27040324.
This paper compares the results of surgical aortic valve replacement with transcatheter aortic valve replacement (TAVR) in intermediate-risk patients.
