Renal replacement therapy in the McMaster Textbook

Renal replacement therapy (RRT), more commonly known as dialysis, is a therapy for the treatment of renal failure and in certain types of poisonings or overdoses. Dialysis can be broadly classified into extracorporeal and peritoneal.

Extracorporeal dialysis involves filtering the circulating blood through a semipermeable membrane in an apparatus outside of the patient’s body.

In peritoneal dialysis, dialysate is instilled into the peritoneal cavity; solutes diffuse from peritoneal capillaries, across the interstitium and mesothelium, into the dialysate. Ultrafiltration of fluid is achieved through an osmotic gradient created by the use of hypertonic dialysate, such as dextrose (glucose monohydrate).

Full text

To access the chapters, go to Renal Replacement Therapy, Hemodialysis, and Peritoneal Dialysis by Dr Karen Chia-Ying To.

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