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Inflammatory polyps (pseudopolyps) arise in inflammatory diseases of the large intestine, most often in ulcerative colitis. Single inflammatory polyps do not undergo malignant transformation. They do not require removal unless they cause bleeding or obstruction or their macroscopic image raises suspicion of dysplasia. Macroscopic characteristics alone (eg, the Narrow-Band Imaging International Colorectal Endoscopic [NICE] classification) are often enough to identify these polyps as inflammatory, in which case removal and histologic examination are not required for diagnosis. Inflammatory polyps are found in diseased colon areas otherwise at risk for cancer and hence need to be differentiated from neoplastic lesions. There is no specific follow-up required after polypectomy.
