Treatment of pregnant women with TSH levels >2.5 mIU/L

Should every pregnant woman with thyroid-stimulating hormone (TSH) levels >2.5 mIU/L be treated with levothyroxine even in the absence of anti-thyroid peroxidase antibodies and antithyroglobulin antibodies?

René Rodríguez-Gutiérrez: The answer to that question is that if [the TSH level] is above 2.5 mIU/L but below the pregnancy reference range and [the patient is antibody-negative], then the recommendation would be not to treat. But if it is over the reference range, which would usually be around 4 or 4.5 mIU/L, with negative antibodies, then you may consider treatment.