McMaster Textbook of Internal Medicine

McMaster Textbook of Internal Medicine
Interviews
Gastroenterology
H pylori eradication before long-term PPI therapy

H pylori eradication before long-term PPI therapy

2018-11-14

Janusz Jankowski

Recorded at the 4th McMaster International Review Course in Internal Medicine (MIRCIM).

Should Helicobacter pylori infection be eradicated before a long-term treatment with proton pump inhibitors (PPIs) is started?

Janusz Jankowski, MD, PhD: The evidence to show that in the absence of causing peptic ulcer disease, chronic gastritis, or mucosa-associated lymphoid tissue (MALT) lymphoma—outside these 3 different classifications—H pylori causes any problems with PPIs is very weak indeed. So the idea of testing to treat it if you are on a long-term PPI is very weak. I would not recommend people do it routinely.

See also

H pylori testing before PPIs in GERD Should patients with symptoms of gastroesophageal reflux disease be tested for Helicobacter pylori before starting proton pump inhibitors (PPIs)?
Endoscopic surveillance in Barrett esophagus How to perform endoscopic surveillance in patients with Barrett esophagus?
Main causes of cirrhosis nowadays What are the main causes of cirrhosis nowadays?
Evaluating H pylori eradication When should we check if Helicobacter pylori eradication therapy was successful? In particular, should we do it in patients with dyspepsia?
Lyophilized fecal material as a pill Do you use lyophilized fecal material in the form of a pill?
Patients at highest risk of C difficile infection What patients are at the highest risk of developing Clostridium difficile infection?
Changing approaches to inflammatory bowel disease management A lecture by Prof. John Marshall, from McMaster University, Canada, delivered at McMaster International Review Course in Internal Medicine in Kraków in May 2016.
Celiac disease and other forms of gluten intolerance in adults A lecture by Prof. Paul Moayyedi, from McMaster University, Canada, delivered at McMaster International Review Course in Internal Medicine in Kraków in May 2016.
Maastricht V: what is new in the management of H pylori infection A lecture by Prof. Peter Malfertheiner, from Otto v. Guericke University, Germany, delivered at McMaster International Review Course in Internal Medicine in Kraków in May 2016.
Indications for long-term PPI treatment What are the indications for long-term treatment with proton pump inhibitors (PPIs)?

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