McMaster Textbook of Internal Medicine

FMT in C difficile infection

2018-04-23

Christine Lee

What is the role of fecal microbiota transplantation (FMT) in the treatment of Clostridium difficile infection?

Christine Lee: The role of fecal microbiota transplantation, also known as FMT, is an attempt to restore healthy microbiota, bacteria, within the colon of individuals who are affected with C difficile infection. The reason why a lot of people with C difficile infection would develop recurrence is because they no longer have protective healthy microbiota. The idea behind FMT is to restore the healthy microbiota, so that the microbiota will be able to combat growth of C difficile infection.

See also

Patients at highest risk of C difficile infection What patients are at the highest risk of developing Clostridium difficile infection?
Diagnosing H pylori-associated dyspepsia After the publication of the Kyoto global consensus report, we are faced with a new entity called Helicobacter pylori-associated dyspepsia. How to make an appropriate diagnosis of this condition?
Causes and prevention of antimicrobial drug resistance What are the causes of antimicrobial drug resistance and can it be prevented? If not, how can we reduce the risk of development of local (eg, in hospitals) or global drug resistance?
Antibiotic resistance: how to handle in clinical practice A lecture by Prof. Mark Loeb, from McMaster University, Canada, delivered at McMaster International Review Course in Internal Medicine in Kraków in May 2016.
Environmental factors affecting inflammatory bowel disease What are the most significant environmental factors affecting the risk and course of inflammatory bowel disease?
Fecal microbiota transplantation in gastrointestinal diseases A review of the use of fecal suspension in saline as treatment of choice to terminate relapsing and severe Clostridium difficile infection.

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