Dr Reza Mirza, rheumatologist, general internist, coauthor of guidelines, and clinical scholar at McMaster University, analyzes the current rheumatology landscape, summarizes data on Janus kinase (JAK) inhibitors, provides an overview of the latest updates in autoinflammatory disease, and comments on the future of rheumatology. The webinar chaired by Dr Madeleine Verhovsek and Dr Margaret Larché was recorded at the Chair’s Medical Grand Rounds on February 2, 2024.